| Player | Matches | Innings | Runs | Avg |
| Kumar Sangakkara (Jamaica Tallawahs) | 2 | 2 | 63 | 63 |
| James Franklin (Guyana Amazon Warriors) | 9 | 8 | 203 | 50.75 |
| Andre Russell (Jamaica Tallawahs) | 9 | 9 | 203 | 50.75 |
| Andre Fletcher (St Lucia Zouks) | 7 | 7 | 238 | 39.66 |
| Justin Kemp (Antigua Hawksbills) | 3 | 3 | 38 | 38 |
| Shoaib Malik (Barbados Tridents) | 8 | 8 | 272 | 34 |
| Lendl Simmons (Guyana Amazon Warriors) | 9 | 9 | 266 | 33.25 |
| Martin Guptill (Guyana Amazon Warriors) | 7 | 7 | 198 | 33 |
| Orlando Peters (Antigua Hawksbills) | 3 | 1 | 31 | 31 |
| Raymon Reifer (Barbados Tridents) | 3 | 3 | 88 | 29.33 |
| Chris Gayle (Jamaica Tallawahs) | 9 | 9 | 234 | 29.25 |
| Danza Hyatt (Jamaica Tallawahs) | 9 | 8 | 145 | 29 |
| Ben Rohrer (Antigua Hawksbills) | 5 | 4 | 85 | 28.33 |
| Chadwick Walton (Jamaica Tallawahs) | 5 | 5 | 137 | 27.4 |
| Marlon Samuels (Antigua Hawksbills) | 7 | 7 | 136 | 27.2 |
| Darren Sammy (St Lucia Zouks) | 7 | 7 | 136 | 27.2 |
| Mohammad Hafeez (Guyana Amazon Warriors) | 7 | 7 | 159 | 26.5 |
| Kieron Pollard (Barbados Tridents) | 8 | 8 | 131 | 26.2 |
| Jahmar Hamilton (Antigua Hawksbills) | 1 | 1 | 24 | 24 |
| Johnson Charles (Antigua Hawksbills) | 7 | 7 | 165 | 23.57 |